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Pure Appl. Chem., Vol. 68, No.5, pp. 1167-1193, 1996

Glossary of Terms Relatings to Pesticides

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macropore Soil pore larger than 1 mm in diameter including interparticle void, earthworm or rodent burrow, drying crack, and decayed root channel. See preferential flow.

margin of safety (MOS) Ratio of the highest estimated or actual level of exposure to a pesticide and the toxic threshold level (usually the NOEC or NOEL). See also uncertainty factor. (US-EPA, 1992)

market basket survey Pesticide residue monitoring on a wide range of food items collected from consumer points of sale and in proportions approximating consumption patterns in the local population. Samples are prepared for analysis according to Codex guidelines i.e. minimal preparation. See also total diet study.

matrix The material or component sampled for pesticide residue studies.

maximum residue limit (MRL) Maximum concentration of a residue that is legally permitted or recognised as acceptable in, or on, a food, agricultural commodity or animal feedstuff as set by Codex or a national regulatory authority. The term tolerance used in some countries is, in most instances, synonymous with MRL. Normally expressed as mg/kg fresh weight. (after FAO, 1986)

maximum tolerated dose (MTD) Highest dose of a pesticide in chronic toxicity testing that is expected, on the basis of sub-chronic studies, to produce only limited toxicity when administered for the duration of the test period. (Duffus, 1993)

median effective concentration (EC50) Statistically derived concentration of a pesticide in an environmental medium expected to produce a certain effect in 50% of the test organisms in a given population under defined conditions. (Duffus, 1993)

median lethal concentration (LC50) Statistically derived concentration of a pesticide in an environmental medium expected to kill 50% of test organisms in a given population under defined conditions. (Duffus, 1993)

median lethal dose (LD50) Statistically derived dose of a pesticide expected to kill 50% of test organisms in a given population under a defined set of conditions. Normally expressed as mg of test material per kg of body weight of the organism. (Duffus, 1993)

mesocosm See model ecosystem.

metabolism Sum total of all physical and chemical processes that take place within an organism; in a narrower sense, the physical and chemical changes that occur for a pesticide within an organism. It includes uptake and distribution within the body, changes (biodegradation), and elimination of pesticides and their metabolites.

metabolites Any intermediate or product resulting from metabolism. (after Duffus, 1993)

microcosm See model ecosystem.

mineralisation Conversion of an element from an organic form to an inorganic form. Mineralisation of pesticides most commonly refers to the microbial degradation to carbon dioxide as a terminal metabolite. See also immobilisation.

model Experimental or mathematical simulation of chemical behaviour in a specific environment. (ASTM, 1984)

model calibration Testing of a model with known input and output information for adjustment or estimation of factors for which data are not available. (ASTM, 1984)

model, computer Assembly of numerical techniques (algorithms), bookkeeping, and control language (i.e. the computer program) comprising a mathematical model and which carries out acceptance of input data and instructions through to delivery of output. (after ASTM, 1984)

model, conceptual Qualitative depiction of a specific environment that describes the linkages between the different compartments. A conceptual model is required before a quantitative simulation model can be developed. (Cohen et al., in press)

model ecosystem Man-made study system containing associated organism and abiotic components that is large enough to be representative of a natural ecosystem, yet small enough to be experimentally manipulated. There is some subjective differentiation between larger, outdoor model ecosystems (mesocosms) and smaller, generally indoor model ecosystems (microcosms).

model validation Comparison of model results with numerical data independently derived from experiments or observations of the environment. (ASTM, 1984)

model verification Examination of the numerical technique in the computer code to ascertain that it truly represents the conceptual model and that there are no inherent numerical problems with obtaining a solution. (ASTM, 1984)

multiresidue method Analytical method which measures a number of pesticide residues simultaneously.

nebulisation Formation of an aerosol of very small liquid particles (fog) or solid particles (smoke) from a pesticide formulation, generally for fumigation of an enclosed space such as a glass-house.

NMR Nuclear magnetic resonance spectroscopy.

non-target organism Organism affected by a pesticide although not an intended object of its use.

no-observable effect concentration/ level (NOEC/NOEL) Highest concentration or amount of pesticide in the test system that causes no observable biological effect to the target organism. (after US-EPA, 1992) See also Ecotoxicologically relevant concentration, PNEC.

NPD Nitrogen-phosphorus detector or detection for gas chromatography (cf AFID and TID).


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