[A]
[B] [C] [D]
[E] [F] [G]
[H] [I-J-K] [L]
[M-N] [O-P] [Q-R]
[S] [T] [U-V]
[W-X-Y-Z]
GC-EC Gas chromatography with electron capture
detector.
GC-MS Gas chromatography-mass spectrometry.
GC-MSD Gas chromatography with mass-selective
detection (usually low resolution mass spectrometry using selected ions).
GLC Gas liquid chromatography.
GLP See Good Laboratory Practice.
GLP Archive Location (room, filing
cabinet etc.) where study plans, raw data, final study reports, laboratory
inspection reports, study audit reports, retention samples or specimens are
stored. GLP records and material must be retained for the period specified
by the appropriate authorities.
GLP Certificate Certificate
of test facility compliance with a national GLP program.
GLP Chain of custody Set of procedures
and traceable records that demonstrate an unbroken control over, or custody
of, a document, or raw data, or a sample from its collection through to its
final disposition.
GLP Compliance statement Declaration
by study director that the study was conducted in compliance with the principles
of GLP and relevant national statutes. Any aspects of non-compliance should
be described in this statement.
GLP Inspection Check of a test
facility, a study or parts of a study by an internal or external authority
to ensure compliance with GLP guidelines. Internal inspections are carried
out by the quality assurance unit. See also GLP study audit.
GLP Principal investigator Person
nominated in the study plan who has the delegated responsibility to
supervise certain phases of a study where the study director cannot
exercise direct control.
GLP Protocol See GLP study plan.
GLP Quality assurance program
Internal control system containing written procedures to ascertain that
studies are in compliance with GLP.
GLP Quality assurance statement
Statement prepared by the quality assurance unit specifying
the dates inspections were made and any findings which were reported to management
and to the study director. This statement is part of the final report of a
study.
GLP Quality assurance unit (QAU)
Sub-section of the test facility, separate from actual testing, responsible
for internal audits of the facility and its Study Reports to ensure
compliance with GLP. The QAU is also generally responsible for the administration
and training in all aspects of the quality assurance system.
GLP Standard operating procedure (SOP)
Written procedure, authorised by management which describe how to perform
a certain routine test or activity normally not specified in detail in study
plans or test guidelines, e.g. arrival, identification and storage of samples,
standards or reagents; operation, maintenance, and calibration of apparatus;
preparation of reagents; quality assurance procedures.
GLP Study Experiment or set of experiments
conducted under GLP.
GLP Study audit Review by the
quality assurance unit of an interim or final report, including raw
data from a study, confirming that the study was carried out in accordance
with the study plan and standard operating procedures and that it has
been accurately and completely reported in compliance with GLP.
GLP Study director The person
responsible for the overall conduct of a study i.e. ensuring that all phases
of the study are conducted under GLP according to the study plan.
GLP Study plan The document
which determines the entire scope of a study conducted under GLP. A written
study plan must be completed and approved by the Study Director before
a study starts. It contains information such as the title of study; name or
code of test and reference substances; name and address of sponsor, test facility,
study director and principal investigators; dates for start and end of study;
methods including relevant standard operating procedures (SOPs); list
of material to be archived.
glucuronides Components resulting
from the conjugation of a pesticide or its metabolite with glucuronic acid.
glycosides Mixed acetals (ketals)
resulting from the conjugation of a pesticide or its metabolite with a saccharide
or saccharide derivative. In plants and insects the saccharide endocon
is commonly an aldohexose.
good agricultural practice (GAP)
Nationally authorised safe uses of pesticides under actual conditions necessary
for effective and reliable pest control. It encompasses a range of levels
of pesticide applications up to the highest authorised use, applied in a manner
that leaves a residue which is the smallest amount practicable. Authorised
safe uses include nationally registered or recommended uses, that take into
account public and occupational health and environmental safety considerations.
Actual conditions include any stage in the production, storage, transport,
distribution and processing of food commodities and animal feed. (IPCS, 1989)
good experimental field practice
The formalised process for designing and recording the practices used
in the performance of field investigations with pesticides, and which assure
the reliability and integrity of the data. See GLP.
good laboratory practice (GLP) The
formalised process and conditions under which laboratory studies on pesticides
are planned, performed, monitored, recorded, reported and audited. Studies
performed under GLP are based on the national regulations of a country and
are designed to assure the reliability and integrity of the studies and associated
data. The US-EPA GLP definition also covers field experiments (see Good
experimental field practice). (After OECD, 1992)
GPC Gel permeation chromatography (cf SEC).
granule Solid formulation comprising
particles of defined size >80mm diameter,
for application without further dilution, usually to soil.
ground water Water present in the saturated
subsurface zone of the soil profile, where all open spaces/pores in the sediment
and rock are filled with water.
guideline level Maximum concentration
of a pesticide residue in or on a feed or food commodity, resulting from a
use reflecting good agricultural practice, but where an acceptable
daily intake has not been estimated.
guideline value Maximum recommended
pesticide residue in an environmental medium that ensures aesthetically pleasing
air, water or food and does not constitute a significant risk to the user.
(after Duffus, 1993)
> Synopsis
> Preface
> References
