COMMISSION ON SEPARATION METHODS IN ANALYTICAL CHEMISTRY
Nomenclature for Non-Linear Chromatography
(IUPAC Recommendations 1996)
Abstract: This report summarizes and comments terms and symbols
used for the description of non-linear chromatography.
In the IUPAC recommendations Nomenclature for Chromatography ,
the conditions of linear chroma-togra-phy are tacitly assumed. In all
versions of chromatogra-phy, however, non-linear effects are common.
These are seen as concentration-dependent retention times and asymmetric
(e.g. tailing or fronting) peaks. Asymmetric peaks can result from a
number of other causes as well, i.e. large extra-column volumes. In
many applications, non-linear effects are disadvantageous as they decrease
peak resolution and disturb quantitative evaluation. However, in prepara-tive
chromatography, heavy overloading is employed in order to increase material
throughput, leading to prominent non-linear effects. A comprehensive
text on non-linear chromatography has recently been published . In
this paper, some of the concepts and terms used for non-linear chromatog-raphy
are described. It is to be read as a complement to the Nomenclature
for Chromatography (CN), to which numerous references are given.
 Recommendations for Nomenclature for Chromatography. Pure Appl.
Chem. 65, 819-872 (1993).
 G. Guiochon, S. Golshan Shirazi and A. M. Katti, Fundamentals of
Preparative and Non-linear Chromatography, Academic Press, Inc. Boston
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