Total synthesis of (�)-clavukerin A
E. L. Grimm, J.-L. Methot, and M. Shamji
Merck Frosst Centre for Therapeutic Research, P.O.Box
1005, Pointe Claire-Dorval, Québec, H9R 4P8 Canada
Abstract: ()-Clavukerin A has been synthesized
via intramolecular Julia coupling and intramolecular sulfone ester cyclization
starting from (+)-limonene oxide.
*Pure Appl.Chem. 75,
141�419 (2003). An issue of reviews and research papers based on
lectures presented at the 23rd IUPAC International Symposium on the
Chemistry of Natural Products, Florence, Italy, 28 July � 2 August 2002.
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