Chemical etiology of nucleic acid structure*
A. Eschenmoser** and R. Krishnamurthy
The Skaggs Institute for Chemical Biology, TSRI, La
Jolla, California 92037, USA; Laboratorium für Organische Chemie,
ETH, CH-8092 Zürich, Switzerland
Abstract: The synthesis of potentially natural nucleic acid
alternatives and comparison of some of their chemical properties with
those of RNA and DNA have led to findings that we consider to be relevant
in the context of a chemical etiology of nucleic acid structure.
*Lecture presented at the 5th International
IUPAC Symposium on Bioorganic Chemistry (ISBOC-5), Pune, India, 30 January
- 4 February, 2000.
**Corresponding author
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