News
& Notices
Organizations & People
Standing
Committees
Divisions
Projects
Reports
..By
Year
..By Division
..Other Committees
..Provisionals
Publications
Symposia
AMP
Links
of Interest
Search
the Site
Home
Page
|
|
Pure Appl. Chem.,
Vol. 65, No. 9, pp. 2003-2122, 1993.
CLINICAL
CHEMISTRY DIVISION
COMMISSION ON TOXICOLOGY
Glossary for chemists of terms used in toxicology
(IUPAC Recommmendations 1993)
Alphabetical entries
A | B | C
| D | E | F
| G | H | I
| J | K | L
| M
N | O | P
| Q | R | S
| T | U | V
| W | X | Y
| Z
ulcer: Defect, often associated with inflammation,
occurring locally or at the surface of an organ or tissue owing
to sloughing of necrotic tissue.
uncertainty
factor:
1. In assay methodology, confidence interval or fiducial limit used
to assess the probable precision of an estimate.
2. In toxicology, value used in extrapolation from experimental
animals to man (assuming that man may be more sensitive) or from
selected individuals to the general population: for example, a value
applied to the no-observed effect level (NOEL) or no-observed adverse
effect level (NOAEL) to derive an acceptable daily intake or reference
dose (RfD) (the NOEL or NOAEL is divided by the value to calculate
the acceptable daily intake or RfD). The value depends on the nature
of the toxic effect, the size and type of population to be protected,
and the quality of the toxicological information available.
SN safety
factor.
RT modifying factor, no-observed-effect-level,
no-observed-adverse-effect-level,
reference dose.
unit risk (as used by the USEPA): Incremental
upper-boundary lifetime risk estimated to result from lifetime exposure
to an agent if it is in air at a concentration of 1 mg/m3 or in
the water at a concentration of 1 mg/L.
IRIS, 1986
upper boundary: Estimate of the plausible
upper limit to the true value of a quantity: this is usually not
a statistical confidence limit.
IRIS, 1986
uptake: Entry of a substance into the body,
into an organ, into a tissue, into a cell, or into the body fluids
by passage through a membrane or by other means.
PS absorption.
urticaria: Vascular reaction of the skin marked by the
transient appearance of smooth, slightly elevated patches (wheals,
hives) that are redder or paler than the surrounding skin and
often attended by severe itching.
A | B | C
| D | E | F
| G | H | I
| J | K | L
| M
N | O | P
| Q | R | S
| T | U | V
| W | X | Y
| Z
Page last modified 12 September 2001.
Copyright ©1997-2001 International Union of Pure and Applied
Chemistry.
Questions or comments about IUPAC, please contact, the Secretariat.
Questions regarding the website, please contact web
manager.
|