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Vol. 27 No. 1
January-February 2005

The Project Place | Information about new, current, and complete IUPAC projects and related initiatives
See also www.iupac.org/projects

Compendium of Targets of the Top 100 Commercially Important Drugs

Published articles on drug discovery frequently point out that most commercially successful pharmaceutical agents act on a relatively small number of molecular targets. However, there does not appear to be a resource where compiled target information is readily available in a single location.

The goal of this project is to provide a resource containing the following information on the targets of the most commercially important drugs: type of target (enzyme, receptor, etc.); brief description of relevance to disease or indication; reference to knockout information, if available; reference to structural information, if available; listing of the marketed drugs that interact with the target along with potency and relevant selectivity information. It is anticipated that this compendium will be a valuable teaching and reference source for the drug discovery community.

For more information, contact the Task Group Chairman, John Proudfoot <jproudfo@rdg.boehringer-ingelheim.com>.

www.iupac.org/projects/2004/2004-025-1-700.html


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