Number: 2000-014-1-700
Title: Recommendations for the use of nanotechnology in clinical
laboratories
Task Group
Chairman: P. Wilding
Members: L. Kricka
Completion Date: 2006 - project completed
Objective:
To provide recommendations for the use of emerging nanotechnology
in the clinical setting. Nanotechnology will offer an increased spectrum
of sophisticated chemical markers at the point of care and high capacity
measurements in the central laboratory.
Description:
The technology that employs micro fabricated devices for biomedical
applications i.e. using sample and reagents in minute amounts e.g.
nanoliter range, has seen an almost exponential growth. The potential
of this technology for analytical purposes in biomedicine has been
demonstrated for immunoassays, the polymerase chain reaction (PCR),
cell isolation, electrophoresis and mass spectrometry. This technology
will also offer large scale screening possibilities for a wide range
of analytes and be applicable outside the traditional laboratory through
the introduction of robust and simplified instruments. The recommendations
will address issues related to traceability of calibrators, transferability
of results and other data performance specifications and quality assessment
Progress:
Project completed - IUPAC Technical Report published in
Pure
Appl. Chem.
78(3), 677-684, 2006
+ errata
(Pure Appl. Chem. 78(5), 1091, 2006)
Last Update: 25 May 2006