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Organizations & People
Pure Appl. Chem.,
Vol. 69, No. 7, pp.1469-1474, 1997
COMMISSION ON SEPARATION METHODS IN ANALYTICAL CHEMISTRY
Analytical chiral separation methods
(IUPAC Recommendations 1997)
Abstract: In recent years there has been considerable interest
in the synthesis and separation of enantiomers of organic compounds
especially because of their importance in the biochemistry and pharmaceutical
industry. Frequently the methods used for the separations, for monitoring
the progress of an asymmetric synthesis or optical purity of the products
are chromatographic with either liquids, gases, or supercritical fluids
as the mobile phase. More recently capillary electrophoresis has been
added as an analytical chiral separation method.
These applications have lead to a number of terms and expressions in
addition to those commonly used or recently recommended for the chemistry
and physical properties of chiral compounds. This Nomenclature provides
the descriptions and definitions for additional terms particularly related
to analytical separation methods, and to the formation and enantiomeric
purity of chiral products.
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