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Pure Appl. Chem., Vol. 65, No. 9, pp. 2003-2122, 1993.



Glossary for chemists of terms used in toxicology
(IUPAC Recommmendations 1993)


Alphabetical entries

A | B | C | D | E | F | G | H | I | J | K | L | M

N | O | P | Q | R | S | T | U | V | W | X | Y | Z



ADI      Acceptable daily intake

ALARA(P) As low as reasonably achievable (practicable)
         In GBR regulations relating to worker exposure
         In USA goal of risk management (USNRC regulations)

ATP      Adenosine triphosphate

BAL      British anti-Lewisite

BATNEEC  Best available technology not entailing excessive cost
         In GBR regulations relating to environmental discharges

BCF      Bioconcentration factor

BEM      Biological effect monitoring

BOD      Biochemical oxygen demand

BPEO     Best practicable environmental option (GBR)

b.w.     Body weight

CLn      See LC

COD      Chemical oxygen demand

DEn      See EDn

DNA      Deoxyribonucleic acid

DNn      See NDn

EC       Enzyme classification number or effective concentration

ECn      Median effective concentration to n % of a population

EDI      Estimated daily intake

EDn      Median effective dose to n % of a population

EEC      Estimated exposure concentration

EED      Estimated exposure dose

EEL      Environmental exposure level

EMDI     Estimated maximum daily intake

EQO      Environmental quality objective

EQS      Environmental quality standard

ERL      Extraneous Residue Limit

ETS      Environmental tobacco smoke

GAP      Good agricultural practice

GLP      Good laboratory practice

GMP      Good manufacturing practice

HSG      Health and Safety Guide (IPCS)

HQ       Hazard quotient

IC       Inhibitory concentration

IDLHC    Immediately dangerous to life or health concentration

i.m.     Intramuscular

inhl     By inhalation

i.p.     Intraperitoneal

IPD      Individual protective devices

I-TEF    International Toxicity Equivalency Factor

i.v.     Intravenous

KOC      Organic carbon partition coefficient

KOW      Octanol water partition coefficient

LCn      Median concentration lethal to n % of a test population

LDn      Median dose lethal to n % of a test population

LEL      Lowest effect level, same as LOEL

LOEL     Lowest observed effect level

LOAEL    Lowest observed adverse effect level

LTn      Median time for death of n % of a test population

LV       Limit value

MCL      Maximum contaminant level (USA - Safe Drinking Water Act)

MCLG     Maximum contaminant level goal (USA - Safe Drinking Water Act)

MAC      Maximum allowable concentration

MEL      Maximum exposure limit

MF       Modifying factor

MOE      Margin of exposure

MRL      Maximum residue limit

mRNA     Messenger ribonucleic acid

MSDS     Material safety data sheet

MTC      Maximum tolerable concentration

MTD      Maximum tolerable dose, Maximum tolerated dose

MTEL     Maximum tolerable exposure level

NADP(H)  Nicotinamide adenine dinucleotide phosphate (reduced)

NDn      Median dose narcotic to n % of a population

NEL      No effect level, same as NOEL

NOAEL    No observed adverse effect level

NOEL     No observed effect level

OEL      Occupational exposure limit

OES      Occupational exposure standard

PEL      Permissible exposure limit

PMR      Proportionate mortality rate, ratio

p.c.     Per cutim (Latin) = Through the skin

p.o.     Per os (Latin) = By mouth

POW      Octanol water partition coefficient

PPD      Personal protective device

PPE      Personal protective equipment

PTWI     Provisional tolerable weekly intake
QSAR     Quantitative structure activity relationship

RD       Rate difference

RfC      Reference concentration

RfD      Reference dose

RME      Reasonable maximum exposure (USEPA)

RNA      Ribonucleic acid

RR       Rate ratio

SAR      Structure-activity relationship

s.c.     Subcutaneous

SCE      Sister chromatid exchange

SMR      Standard mortality ratio

SNARL    Suggested no adverse response level

STEL     Short term exposure limit

t1/2     Half-life

TCDD     2,3,7,8-tetrachlorodibenzo-p-dioxin

TDI      Tolerable daily intake

TEF      Toxicity equivalency factor

TEQ      Toxicity equivalent

TLn      See LTn

TLV      Threshold limit value

TMDI     Theoretical maximum daily intake

TSEL     Tentative safe exposure level

TWA      Time-weighted average

TWAC     Time-weighted average concentration

TWAE     Time-weighted average exposure

UF       Uncertainty factor

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Alphabetical entries

A | B | C | D | E | F | G | H | I | J | K | L | M

N | O | P | Q | R | S | T | U | V | W | X | Y | Z

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