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Chemistry International
Vol. 24, No. 2
March 2002


New Books and Publications

CRC Handbook of Optical Resolutions via Diastereomeric Salt Formation

Dávid Kozma (Ed.) CRC Press, September 2001, pp. 800. (ISBN 0-8493-0019-3)

Optically active compounds are gaining ever-increasing importance in organic chemistry, both in the academic and the industrial arenas. The rational synthesis of the growing number of chiral chemicals, drugs, and natural products demands efficient methods for producing these compounds in an enantiomerically, highly pure form. Despite the available alternative techniques, optical resolution via diastereomeric salt formation remains the most widely used method of preparing pure enantiomers.

This is the first book to exclusively address this important organic chemical process. It provides fast, one-stop access to a wealth of information, including all of the available data on 100 resolving agents, a list of 500 optically active compounds available in bulk and a list of their suppliers, data on more than 3500 resolutions, and 4200 citations. With an abundance of analyzed examples, this single, authoritative reference provides all of the information necessary to perform, develop, and optimize optical resolutions via diastereomeric salt formation.






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